11. Degenerative joint disease is a leading source of morbidity resulting in significant social and economic impact. 12. It is also called degenerative joint disease . 13. Extreme joint instability, chronic musculoskeletal pain, degenerative joint disease , frequent injuries, and spinal deformities may limit mobility. 14. This Marlow-- like Potter-- has a debilitating skin and joint disease and is confined to a hospital bed. 15. "' Bone Medical "'is a small Perth-based biopharmaceutical company aiming to develop medicines for bone and joint disease . 16. Cousins suffered from a life-threatening joint disease and reported that 10 minutes of laughter helped reduce his pain. 17. Osteoarthritis is a joint disease that causes the cushion layer between one's bones, or cartilage to wear away. 18. Unless he sheds a few pounds, Santa's extra weight may lead to a painful joint disease known as osteoarthritis. 19. The supplements are marketed as treatments for osteoarthritis, the degenerative joint disease that afflicts about 21 million people nationwide. 20. For example, he said, the most common form of arthritis, osteoarthritis, is also called " degenerative joint disease ."