Inhibition of kynurenine 3-monooxygenase leads to an increase of kynurenic acid in the kynurenine pathway.
12.
Inhibition of kynurenine 3-monooxygenase leads to an increase of kynurenic acid in the kynurenine pathway.
13.
Quinolinic acid is a downstream product of the kynurenine pathway, which metabolizes the amino acid tryptophan.
14.
Quinolinic acid is a byproduct of the kynurenine pathway, which is responsible for catabolism of tryptophan in mammals.
15.
As the main defect behind hypertryptophanemia is suspected to alter and disrupt the metabolic pathway from tryptophan to kynurenine,
16.
Kynureninase catabolizes the conversion of kynurenine into anthranilic acid while kynurenine-oxoglutarate transaminase catabolizes its conversion into kynurenic acid.
17.
Kynureninase catabolizes the conversion of kynurenine into anthranilic acid while kynurenine-oxoglutarate transaminase catabolizes its conversion into kynurenic acid.
18.
Indirectly related to kynurenine metabolism, indole modifies neural function and human behavior by interacting with synaptic action potentials ).
19.
Another function of GOT2 is that it is believed to transaminate kynurenine into kynurenic acid ( KYNA ) in the brain.
20.
This action is in opposition to the agonist quinolinic acid, another kynurenine, noted for its potential as a neurotoxin.
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