11. Osteocalcin acts on Leydig cells of the testis to stimulate testosterone biosynthesis and therefore affect male fertility. 12. Immunohistochemical markers of Leydig cell tumours include inhibin-alpha, calretinin, and melan-A. 13. LH stimulates the Leydig cells of the testes to make testosterone and blood levels begin to rise. 14. Leydig cells will work for testosterone production if " transplanted " into castrated male mice.15. CB 1 is present on Leydig cells and human ovaries, oviducts myometrium, decidua, and placenta. 16. Sections of testicular tissue from rat revealed positive immunoreactivity against anti-inhibin intensely appeared in Leydig cells . 17. However, a faint positive reaction was detected in Leydig cell cytoplasm in rats treated with anise oil. 18. The testes have two primary functions : to produce hormones and to produce Sertoli and Leydig cells ). 19. Leydig cells are located in the testis and known for the function as a support cell in spermatogenesis.20. Testicular cancer, Leydig cell tumours and Sertoli cell tumours are also associated with reduced sperm count and quality.
