Sex-linked inheritance of a mutation causing white eyes in " Drosophila " led him to the hypothesis that genes are located upon chromosomes . ]]
12.
In X-linked inheritance, all offspring of a carrier female have a 50 % chance of inheriting the mutation if the father does not also carry the mutation.
13.
The somatic, or X-linked inheritance patterns of RP are currently identified with the mutations of six genes, the most common occurring at specific loci in the RPGR and RP2 genes.
14.
In addition to families with well defined X linked inheritance, TBX22 mutations have been identified in several families where pedigree size and / or family history were too limited to predict mode of inheritance.
15.
Clinical suspicion for X-linked inheritance would be a disease affecting multiple boys ( but no girls ) and a pedigree chart showing inheritance only through the maternal ( mother s ) side of each generation.
16.
As the X chromosome is one of the sex chromosomes ( the other being the Y chromosome ), X-linked inheritance is determined by the sex of the parent carrying a specific gene and can often seem complex.
17.
The family tree ( with affected members ) is well-known and demonstrates X-linked inheritance . . . there may or may not be a copy somewhere on Wikipedia .-Nunh-huh 06 : 15, 19 October 2005 ( UTC)
18.
Some scholars have suggested discontinuing the terms dominant and recessive when referring to X-linked inheritance due to the multiple mechanisms that can result in the expression of X-linked traits in females, which include cell autonomous expression, skewed X-inactivation, clonal expansion, and somatic mosaicism.
19.
These disorders are characterized by autosomal-dominant mode of inheritance ( with the exception of spino-bulbar muscular atrophy, which shows X-linked inheritance ), midlife onset, a progressive course, and a correlation of the number of CAG repeats with the severity of disease and the age at onset.
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