Lipogenesis encompasses both the process of fatty acid synthesis and triglyceride synthesis ( where fatty acids are esterified to glycerol ).
12.
In mammals, PC plays a crucial role in gluconeogenesis and lipogenesis, in the biosynthesis of neurotransmitters, and in glucose-induced insulin secretion by pancreatic islets.
13.
More specifically, a low concentration in the free acid component of the serum indicates a risk of metabolic disease, and that de novo lipogenesis should be stimulated.
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SIRT2-mediated deacetylation and activation of G6PD stimulates oxidative branch of PPP to supply cytosolic NADPH to counteract oxidative damage or support " de novo " lipogenesis.
15.
The acetyl-CoA " can " go to energy via the citric acid cycle, but since we're talking fat here we want lipogenesis instead.
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Co-culturing 3T3-L1 pre-adipocytes in 3D with murine endothelial bEND . 3 cells creates a vascular-like network assembly with concomitant lipogenesis in perivascular cells.
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Liver-specific disruption of mTORC2 through hepatic deletion of the gene " Rictor " leads to glucose intolerance, hepatic insulin resistance, decreased hepatic lipogenesis, and decreased male lifespan.
18.
In the liver, ChREBP mediates activation of several regulatory enzymes of glycolysis and lipogenesis including L-type pyruvate kinase ( L-PK ), acetyl CoA carboxylase, and fatty acid synthase.
19.
The liver plays several roles in lipid metabolism : it performs cholesterol synthesis, lipogenesis, the production of triglycerides, and a bulk of the body's lipoproteins are synthesized in the liver.
20.
PDE then will inhibit cyclic AMP ( cAMP ) action and cause inactivation of PKA which will cause Hormone Sensitive Lipase ( HSL ) to be dephosphorylated and inactive so that lipolysis and lipogenesis is not occurring simultaneously.
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