As the cancer metastasizes to other parts of the body, prognosis drops dramatically because treatment of local lesions is generally more effective than whole-body treatments such as chemotherapy.
12.
Under moist conditions, the pathogen sporulates on the affected tissues and spreads to other plants, on the leaves and stalks of which it forms greyish-violet local lesions.
13.
It struck me that this theory [ of immunological hypersensitivity as the etiology of the Aschoff nodule ] had never been tested and indeed could not be tested without the demonstration of antibody or antigen, preferably both, in the local lesions.
14.
After a mild fever and the expected local lesion James recovered after a few days . About two months later Jenner inoculated James on both arms with material from a case of smallpox, with no effect; the boy was immune to smallpox.
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