11. Analyses have revealed a mixture of biopolymers, containing mainly long chain fatty acids , phenylpropanoids, phenolics and traces of carotenoids. 12. A non-functional D-BP protein results in the abnormal accumulation of long chain fatty acids and bile acid intermediates. 13. Beta-oxidation of long chain fatty acids produces two carbon units, acetyl-CoA and the reducing equivalents NADH and FADH2. 14. The very long chain fatty acid ( > 18 carbon atoms ) content ranged from 0.44 to 1.37 %. 15. This results in the over-accumulation of very long chain fatty acids and branched chain fatty acids, such as phytanic acid. 16. It is an elongase that appears to be involved in the production of very long chain fatty acids that are 26 carbons and longer. 17. In X-ALD patients, abnormally high levels of very long chain fatty acid ( VLCFA ) accumulate in various body tissues and fluids. 18. Bulkier long chain fatty acids are bound by a fatty acid-binding tunnel that is located in the N-terminal domain of each monomer. 19. It is classified in the sub-group of very long chain fatty acids ( VLCFA ), which includes molecules containing more than 20 carbon atoms. 20. Biochemically, individuals with ALD show very high levels of unbranched, saturated, very long chain fatty acids , particularly cerotic acid ( 26 : 0 ).
