11. A mutation in the A region results in a complete loss of function . 12. Loss of function of LH receptors can cause male pseudohermaphroditism.13. Adaptive contraction of gene families commonly results from accumulation of loss of function mutations. 14. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome.15. GSH mutations or deletions result in loss of function and result in decreased detoxification. 16. Genetic polymorphisms in these enzymes may induce loss of function or gain of function. 17. But when selection is weak, mutation bias towards loss of function can affect evolution. 18. The result is loss of function , which affects mRNA stability. 19. The formation of illegitimate sulfide bonds creates a misfolded protein, resulting in loss of function . 20. Loss of function of this protein significantly increases the strength and power of mouse muscles.
