Another definition presented by Elliot et al . includes the presence of either three major features ( anterior abdominal wall defect, macroglossia, or prepostnatal overgrowth ) or two major plus three minor findings ( ear pits, nevus flammeus, neonatal hypoglycemia, nephromegaly, or hemihyperplasia ).
12.
"' Macroglossia "', a large tongue, is a very common ( > 90 % ) and prominent feature of BWS . Infants with BWS and macroglossia typically cannot fully close their mouth in front of their large tongue, causing it to protrude out.
13.
"' Macroglossia "', a large tongue, is a very common ( > 90 % ) and prominent feature of BWS . Infants with BWS and macroglossia typically cannot fully close their mouth in front of their large tongue, causing it to protrude out.
14.
It is not a disease as such, but usually results from habits where the tongue is pressed against the lingual surfaces ( the side facing the tongue ) of the dental arches, or from any cause of macroglossia ( enlarged tongue ), which in itself has many causes such as Down syndrome.
15.
And after Drs Beckwith and Wiedemann described a syndrome of low blood sugar, omphalocele abdominal malformation and macroglossia ( enlarged tongue ), Drs Winter and Curry and colleagues discovered how the syndrome, which had been named Beckwith-Wiedemann Syndrome, could be diagnosed prenatally ( before the baby was born ).
16.
Originally, Dr . Hans-Rudolf Wiedemann ( born 16 February 1915, Bremen, Germany, died 4 August 2006, Kiel ) coined the term exomphalos-macroglossia-gigantism ( EMG ) syndrome to describe the combination of congenital exomphalos ), large tongues ( macroglossia ), and large bodies and / or long limbs ( gigantism ).
17.
Originally, Dr . Hans-Rudolf Wiedemann ( born 16 February 1915, Bremen, Germany, died 4 August 2006, Kiel ) coined the term exomphalos-macroglossia-gigantism ( EMG ) syndrome to describe the combination of congenital exomphalos ), large tongues ( macroglossia ), and large bodies and / or long limbs ( gigantism ).
18.
In an attempt to standardize the classification of BWS, DeBaun et al . have defined a child as having BWS if the child has been diagnosed by a physician as having BWS and if the child has at least two of the five common features associated with BWS ( macroglossia, macrosomia, midline abdominal wall defects, ear creases / ear pits, neonatal hypoglycemia ).
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