Pheochromocytoma ( PCC ) is a rare, but potentially lethal ( if unnoticed and it leads to malignant hypertension or hypertension ) condition and can be misdiagnosed as straightforward hypertension.
12.
However, while the menace of severe or malignant hypertension was well recognised, the risks of more moderate elevations of blood pressure were uncertain and the benefits of treatment doubtful.
13.
The renal lesion associated with malignant hypertension consists of fibrinoid necrosis of the afferent arterioles, sometimes extending into the glomerulus, and may result in focal necrosis of the glomerular tuft.
14.
A pheochromocytoma can be fatal if it causes a hypertensive emergency, that is, severely high blood pressure that impairs one or more organ systems ( formerly called " malignant hypertension " ).
15.
Sodium nitroprusside, a very potent, short-acting vasodilator, is most commonly used for the quick, temporary reduction of blood pressure in emergencies ( such as malignant hypertension or aortic dissection ).
16.
Soon after, while watching England lose to Scotland at rugby on television, a glass of whisky in his hand, he died at home of a heart attack brought about by malignant hypertension, aged just 46.
17.
In addition, non-pharmacological treatment could be considered in cases of resistant malignant hypertension due to end stage kidney failure, such as surgical nephrectomy, laparoscopic nephrectomy, and renal artery embolization in cases of anesthesia risk.
18.
Common sites undergoing fibrinoid necrosis are, SLE, Aschoff bodies seen in rheumatic heart disease, Arthus reaction, serum sickness, polyarteritis nodosa, poststreptococcal glomerulonephritis, hyperacutely rejected grafts, malignant hypertension ( > 200 / 130 mm Hg ).
19.
In 1928, the term malignant hypertension was coined by physicians from the Mayo Clinic to describe a syndrome of very high blood pressure, severe retinopathy and adequate kidney function which usually resulted in death within a year from strokes, heart failure or kidney failure.
20.
Symptoms of scleroderma renal crisis are malignant hypertension ( high blood pressure with evidence of acute organ damage ), hyperreninemia ( high renin levels ), azotemia ( kidney failure with accumulation of waste products in the blood ) and microangiopathic hemolytic anemia ( destruction of red blood cells ).
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