Keratinocytes contribute to skin pigmentation holding the melanin originated in melanocytes and induce melanogenesis through chemical signals directed at melanocytes.
12.
Also taxifolin inhibited the cellular melanogenesis as effectively as arbutin, one of the most widely used hypopigmenting agents in cosmetics.
13.
6-nitroquipazine has been found to inhibit melanogenesis in-vitro, suggesting that it can be used for skin whitening.
14.
The tan that is created by an increased melanogenesis lasts much longer than the one that is caused by oxidation of existing melanin.
15.
Whilst not all of these genes directly affect melanin production, most of them code for proteins that may play a significant role in melanogenesis and control melanin concentration.
16.
The cuboidal cells within LAM lesions also react with a monoclonal antibody called HMB-45, developed against the premelanosomal protein gp100, an enzyme in the melanogenesis pathway.
17.
The melanogenesis produced by melanotan II is caused by activation of the MC 1 receptor, whereas its loss of appetite ( the last via activation of MC 4 ).
18.
The researchers who identified the mutation in 2008 suggested that melanosome pH may be affected, which in turn might affect the processing of tyrosine, a critical element of melanogenesis.
19.
The synthesis of melanin ( also called " melanogenesis " and " melanization " ) involves a chain of enzyme-catalyzed chemical reactions and non-enzyme-catalyzed reactions.
20.
Mutually, boosting magnesium ascorbyl phosphate derived Vitamin C and La Prairie's Skin Whitening Complex bond with the tyrosinase enzyme, de-activating it and inhibiting melanogenesis or melanin formation.
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