The symptoms of type II Griscelli syndrome have shown that Rab27 is involved in melanosome transport in melanocytes and in cytotoxic killing activity in cytotoxic T lymphoblasts.
12.
Small amounts of melanin-like granules together with other electrone-dense particles can also be seen within large melanosome complexes in the underlying connective tissue.
13.
They have a characteristic ultrastructure on electron microscopy, which varies according to the maturity of the melanosome, and for research purposes a numeric staging system is sometimes used.
14.
If present, the mesosome, intermediate in color between a leucosome and melanosome, is mostly a more or less unmodified remnant of the original parent rock ( protolith ).
15.
The researchers who identified the mutation in 2008 suggested that melanosome pH may be affected, which in turn might affect the processing of tyrosine, a critical element of melanogenesis.
16.
By examining melanosome structure and distribution, Zhang and colleagues were able to confirm the presence of light and dark bands of colour in the tail feathers of " Sinosauropteryx ".
17.
Until recently, it was believed that the probable ligand for OA1 might be within the melanosomal lumen, maybe one of the components of the melanogenic pathway since it is so closely related to melanosome biogenesis.
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