11. Methionine synthase reductase regenerates a functional methionine synthase via reductive methylation. 12. Methionine directly affects S-adenosyl methionine ( SAM ) levels.13. Methionine directly affects S-adenosyl methionine ( SAM ) levels. 14. Methionine is a protein substitute added mainly to poultry and pig feed.15. Degussa AG ( 2002 ), methionine cartel, 118 million euros. 16. For example, cyanogen bromide cleaves the peptide bond after a methionine . 17. A 2005 study showed methionine restriction without energy restriction extends mouse lifespan. 18. Administration of methionine ameliorated the pathological consequences of methionine deprivation. 19. Administration of methionine ameliorated the pathological consequences of methionine deprivation. 20. The consequence of reduced methionine synthase activity is megaloblastic anemia. 