These studies defined the genomic landscapes of human cancers and identified alterations in a variety of genes and pathways not previously known to be involved in tumorigenesis, including the IDH1 and IDH2 genes in gliomas [ 16 ], and chromatin modifying genes MLL2 / 3 and ARID1 in medulloblastomas, neuroblastomas and other tumor types [ 18-20 ].
12.
These foals would have inherited one copy of the cream dilution gene from their sire, and their base colour from their mothers, but the unusual colours mentioned indicate that the'silver'brumby carried other colour modifying genes in addition to the cream dilution gene, potentially including the silver dapple gene ( which results in taffy ), the dun gene or the flaxen gene.
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