11. By contrast, the three most significant bits ( MSBs ) stay unchanged ( 000 to 000 ). 12. Bits 17A 51A encode the time of the following minute in binary-coded decimal, most significant bit first. 13. To obtain extended function information CPUID should be called with the most significant bit of EAX set. 14. It begins with the most significant bit of the number of layers, and ends with the check words. 15. Numbers greater than the maximum possible encoded value have their most significant bits chopped off until they fit. 16. Something like 192.168.1 . 0 / 20 will use the 20 most significant bits of 192.168.1 . 0. 17. On the other hand, floppy disks and most hard drives write the most significant bit of each byte first. 18. The integer binary logarithm can be interpreted as the zero-based index of the most significant bit in the input. 19. Note that the penultimate bit is the most significant bit and the first bit is the least significant bit. 20. With the most significant bit set the character is generated in inverse video; corresponding to code points 128 191.