Ion-exchange chromatography is also useful in the isolation of specific multimeric protein assemblies, allowing purification of specific complexes according to both the number and the position of charged peptide tags.
12.
The binding site of the MCD peptide on the K + ion channel protein complex is a multimeric protein, consisting of polypeptide chains of molecular weight between 76, 000-80, 000 and 38, 000 Daltons.
13.
The Signal recognition particle ( SRP ) is a multimeric protein, which along with its conjugate receptor ( SR ), is involved in targeting secretory proteins to the rough endoplasmic reticulum ( RER ) membrane in eukaryotes, or to the plasma membrane in prokaryotes.
14.
The allosteric regulators merely shift the equilibrium between the conformations, stabilizing the ones for which they display the highest affinity, and 2 ) all the subunits of a symmetrical multimeric protein exist in the same conformation, the transition taking place in a " concerted " fashion.
15.
Thus, in the nucleotide model proposed by Dickinson, AG and lifecycle of the scrapie agent included a stage where the genome was bound to host protein, probably a multimeric protein complex ( now commonly known as a prion ), derived from the " sinc " gene.
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