The ASCO study showed 52 % posterior fossa; 39 % sPNET ( supratentorial primitive neuroectodermal tumors ); 5 % spinal, and 2 % multi-focal.
12.
The diseases are, however, considered to be different : peripheral primitive neuroectodermal tumours are generally not associated with bones, while Ewing sarcomas are most commonly related to bone.
13.
"' Zunich Kaye syndrome "', also known as "'Zunich neuroectodermal syndrome "', is a rare congenital ichthyosis first described in 1983.
14.
Historically medulloblastomas have been classified as a PNET ( primitive neuroectodermal tumour ), however it is now known that medulloblastoma is distinct from supratentorial PNET's and are no longer considered similar entities.
15.
Nonetheless, the NGcGM3 ganglioside is highly expressed in several human cancers, including lung, breast, melanocytes, colon and neuroectodermal pediatric tumors, making this neoantigen an attractive target for cancer therapy.
16.
BRD4 enhances this activation by recruiting P-TEFb; if either BRD4 or P-TEFb is not functional, pluripotent gene transcription is blocked, and the cell differentiates into a neuroectodermal cell.
17.
The terminal differentiation of some somatic stem cells has recently been called into question after studies of transplanted haematopoietic stem cells showed the development of myoblasts, endothelium, epithelium and neuroectodermal cells, suggesting pluripotency.
18.
DSRCT shares characteristics with other small-round blue cell cancers including Ewing's sarcoma, acute leukemia, small cell mesothelioma, neuroblastoma, primitive neuroectodermal tumor, rhabdomyosarcoma, and Wilms'tumor.
19.
Since a common genetic locus is responsible for a large percentage of Ewing's sarcoma and primitive neuroectodermal tumors, these are sometimes grouped together in a category known as the Ewing family of tumors.
20.
In addition, inherited uni-or bilateral retinoblastomas may be associated with pineoblastoma and other malignant midline supratentorial primitive neuroectodermal tumors ( PNET ) with a dismal outcome; retinoblastoma concurrent with a PNET is known as trilateral retinoblastoma.
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