Binding of acetylcholine to receptors on the end-plate causes depolarization and contraction of the muscle fiber; non-depolarizing neuromuscular blocking agents like pancuronium stop this binding from taking place.
12.
Some conscious patients who are administered neuromuscular blocking agents such as succinylcholine may have low bispectral index scores; thus, the BIS may fail to detect consciousness in such patients.
13.
Attorney Jeffrey Bronster said Pelissier never used the neuromuscular blocking agent to euthanize an animal, but has used it to sedate animals that were difficult to control for his and the animals'safety.
14.
The lawsuit emphasizes the American Veterinary Medical Association's ban on the combination of a sedative with a neuromuscular blocking agent and contends that a euthanasia practice considered unfit for a dog shouldn't be used for humans.
15.
Mivacurium is a biodegradable neuromuscular blocking agent owing to its degradation by plasma cholinesterases-the esterases rapidly hydrolyze one ester moiety initially resulting in a two mono-quaternary metabolites of which one still has an intact ester moiety.
16.
C-toxiferine I itself has been tested for its pharmacological action and noted to be a very long acting neuromuscular blocking agent For a formal definition of the durations of actions associated with NMB agents, see page for gantacurium.
17.
Roy Washburn, who notes that D-Tubocurarine, a neuromuscular blocking agent used to relax muscles during general anaesthesia, was found in her car and in her companion's body, and the companion wasn't breathing at the time of the crash, and that a man named " Dicky Pep " said that he sold Tramell " 15 milliliters of DTC last Thursday ".
18.
Present clinical anesthetic practice still employs the central principle of balanced anesthesia though with some differences to accommodate subsequent technological advances and introductions of new and better gaseous anesthetic, hypnotic and neuromuscular blocking agents, and tracheal intubation, as well as monitoring techniques that were nonexistent in the day of Gray and Halton : pulse oximetry, capnography, peripheral nerve stimulation, noninvasive blood pressure monitoring, etc.
19.
There was complete failure to disseminate the true picture that these effects were not only transient but that the extent of the hypotensive effect and the reflex tachycardia were rarely of clinical significance and therefore did not require adjunctive therapy, as evidenced by the complete lack of any clinical literature advocating the need for adjunctive antihistamine use concomitantly with the administration of tetrahydroisoquinolinium neuromuscular blocking agents.
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