11. The C-terminal region of XPF includes the active site residues for nuclease activity. 12. The mode of action appears to be nuclease activity resulting in the induction of apoptosis. 13. This sequence feature adopted a highly distorted conformation as shown by its response to nuclease enzymes. 14. They termed the nuclease enzyme RISC. 15. TNA has generated great interest in synthetic biology because TNA polymers are resistant to nuclease degradation. 16. Nuclease protection assays are used to map introns and transcription of the gene in the cell.17. Transposon can appear at other locus through transcription or reverse transcription by the effect of nuclease . 18. The ERCC1 XPF nuclease incises the damaged DNA strand on the 52 side of the lesion. 19. PIN domains function as nuclease enzymes that cleave single stranded RNA in a sequence dependent manner. 20. The natural properties of these pathways form the very basis of nuclease -based genome editing.