11. One in 70000 adults has an ornithine transcarbamylase deficiency. 12. Specifically, arginase converts L-arginine into L-ornithine and urea. 13. Mutations in the " SLC25A15 " gene cause ornithine translocase deficiency. 14. Ornithine aminotransferase forms the initial intermediate in this process.15. The separate pathways of converting ornithine to putrescine in plants and animals have converged. 16. Biochemically, it can be detected by elevated levels of ornithine in the blood. 17. These are lysine, arginine, and ornithine . 18. Biosynthesis begins with decarboxylation of ornithine by ornithine decarboxylase ( ODC ) to produce putrescine. 19. Biosynthesis begins with decarboxylation of ornithine by ornithine decarboxylase ( ODC ) to produce putrescine. 20. Ornithine decarboxylase can catalyse the decarboxylation of DFMO instead of ornithine, as shown above.
