It has been confirmed that Patent ductus arteriosus-bicuspid aortic valve syndrome is a distinct syndrome from an allelic variant of Char syndrome.
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Common defects include atrial septal defect, tetralogy of Fallot, ventricular septal defect, patent ductus arteriosus, pulmonary stenosis, and coarctation of the aorta.
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Patent ductus arteriosus, where blood is channelled back from the heart into the lungs, is also seen and can lead to heart failure.
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Failure of the DA to close after birth results in a condition called patent ductus arteriosus and the generation of a left-to-right shunt.
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"Transumbilical catheter intervention " is also a method of gaining access to the heart, for example to surgically correct a patent ductus arteriosus.
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It should be avoided near term in a pregnant woman because of the risk of having a patent ductus arteriosus in the neonate.
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Holt Oram syndrome, Brachydactyly-long thumb syndrome, Patent ductus arteriosus-bicuspid aortic valve syndrome and Heart-hand syndrome, Slovenian type are known to be autosomally dominant disorders.
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