11. Chromaffin paragangliomas are issued from chromaffin cells, and are known as pheochromocytomas . 12. Surgery, especially adrenal laparoscopy, is the most common treatment for small pheochromocytomas . 13. A pheochromocytoma can also cause resistant arterial hypertension. 14. The patient with pheochromocytoma is invariably volume depleted. 15. Extra-adrenal tumors account for around 10 % of all cases of pheochromocytoma . 16. The same condition is often called familial pheochromocytoma . 17. Pheochromocytoma may occur in patients with MEN 2 and MEN 3 ( MEN 2B ).18. Both syndromes are characterized by pheochromocytoma as well as thyroid cancer ( thyroid medullary carcinoma ). 19. Therefore, it is usually advised to " salt load " pheochromocytoma patients before their surgery. 20. Other disorders that can cause high blood pressure include thyrotoxicosis, pheochromocytoma , and drug misuse.