11. It is also dependent on several microtubule-associated proteins such as adenomatous polyposis coli ( APC ). 12. Familial adenomatous polyposis ( FAP ) is caused by an inherited, inactivating mutation in the APC gene. 13. The most common mutation in familial adenomatous polyposis is a deletion of five bases in the APC gene. 14. This approach was used in 2012 in clinical trials to try to treat patients with Familial Adenomatous Polyposis . 15. Is a Japanese geneticist best known for identifying the tumor suppressor gene APC responsible for Familial Adenomatous Polyposis . 16. In familial adenomatous polyposis , the abnormality is a mutation in the APC gene, resulting in its inactivity. 17. Related polyposis conditions are familial adenomatous polyposis, attenuated familial adenomatous polyposis, Birt Hogg Dub?syndrome and MUTYH. 18. Related polyposis conditions are familial adenomatous polyposis , attenuated familial adenomatous polyposis, Birt Hogg Dub?syndrome and MUTYH. 19. Related polyposis conditions are familial adenomatous polyposis, attenuated familial adenomatous polyposis , Birt Hogg Dub?syndrome and MUTYH. 20. Like the adenomatous polyposis mutation, the new mutation was also producing truncated APC proteins but by a novel mechanism.
