For these reasons, it is important that infants with infantile hemangiomas be evaluated by an appropriate clinician during the early proliferative phase so that risk monitoring and treatment be individualized and outcomes can be optimized.
12.
During the early proliferative phase ( 0 12 months ) the tumors express proliferating cell nuclear antigen ( pericytesna ), vascular endothelial growth factor ( VEGF ), and type IV collagenase, the former two localized to both endothelium and pericytes, and the last to endothelium.
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