Other Schedule IV narcotics also include butorphanol nasal spray, pentazocine, propoxyphene-based mixtures and others of the same type.
12.
In addition, both propoxyphene and its metabolite norpropoxyphene have local anesthetic effects at concentrations about 10 times those necessary for opioid effects.
13.
Lyric of Light, was subsequently disqualified after a post-race urine sample revealed traces of Propoxyphene, a prohibited analgesic substance.
14.
For moderate pain, tramadol, codeine, dihydrocodeine, and hydrocodone are used, with nicocodeine, ethylmorphine and propoxyphene and dextropropoxyphene less commonly.
15.
Excessive opioid receptor stimulation is responsible for the CNS depression, respiratory depression, aspiration pneumonia, miosis, and gastrointestinal effects seen in propoxyphene poisoning.
16.
Both propoxyphene and norpropoxyphene are potent blockers of cardiac membrane sodium channels and are more potent than lidocaine, quinidine, and procainamide in this respect.
17.
However, the European Medicines Agency has recently backed the agency's decision, and recommended in June 2009 that propoxyphene preparations be withdrawn across the European Union.
18.
On November 19, 2010, the FDA requested manufacturers withdraw propoxyphene from the US market citing to heart arrhythmia in patients who took the drug at typical doses.
19.
More than 1.3 million older Americans had prescriptions for propoxyphene, an addictive narcotic that, the authors say, is no better than aspirin in relieving pain.
20.
Widening of the QRS complex appears to be a result of a quinidine-like effect of propoxyphene, and sodium bicarbonate therapy appears to have a positive direct effect on the QRS dysrhythmia.
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