11. Coagulase reacts with prothrombin in the blood. 12. Prothrombin time ( PT ) was above 10013. Individuals who carry the condition have the prothrombin mutation which can be inherited by offspring. 14. The prothrombin time ( PT ) and partial thromboplastin time ( PTT ) is often prolonged. 15. Warfarin and related drugs inhibit vitamin K-dependent carboxylation of several coagulation factors, including prothrombin . 16. Prothrombin time, activated partial thromboplastin time, thrombin time, and fibrinogen tests should be performed.17. He named the hypothetical enzyme " thrombin ", and he called its precursor " prothrombin ". 18. Some older reference works substitute Prothrombin time ( PT ) prolongation for International normalized ratio ( INR ). 19. It acts by cleaving prothrombin in two places ( an co-factor V in the prothrombinase complex. 20. Factor V Leidan and mutations of the prothrombin gene are the two most common genetic causes of hypercoagulability.