11. "' Quinoline Yellow SS "'is a bright yellow dye with green shade. 12. The quinoline and quinuclidine rings are sterically demanding groups that can induce a high degree of stereoselectivity. 13. At that time, each quinoline yellow was allowed in puddings and desserts, but tartrazine was not. 14. Quinoline is only slightly soluble in cold water but dissolves readily in hot water and most organic solvents.15. Isoquinoline and quinoline are benzopyridines, which are composed of a benzene ring fused to a pyridine ring. 16. As with other quinoline antimalarial drugs, the mechanism of action of quinine has not been fully resolved. 17. The best-understood examples of such hematin biocrystallization inhibitors are quinoline drugs such as chloroquine and mefloquine. 18. The basic pharmacophore, or active structure, of the fluoroquinolone class is based upon the quinoline ring system. 19. After his return to Germany, Hofmann continued to experiment with dyestuffs, finally creating quinoline red in 1887. 20. Reaction of N-acyl isatins with base gives 2-hydroxy-quinoline -4-carboxylic acids.
