Sarcosine-treated patients were much more likely and quicker to remit and less likely to drop out of the study.
12.
Under anaerobic condition and without tetrahydrofolate, however, a free formaldehyde is formed after the N-demethylation of sarcosine.
13.
:N, N-dimethylglycine + H 2 O + O 2 \ rightleftharpoons sarcosine + formaldehyde + H 2 O 2
14.
Prior to the synthesis of sarcosine, it had long been known to be hydrolysis product of creatine, a compound found in meat extract.
15.
Under this assumption, Volhard proposed that sarcosine was N-methylglycine, and proved so by preparing the compound with methylamine and monochloroacetic acid.
16.
Handler also provided an understanding of the oxidation of sarcosine to glycine and formaldehyde which led to the importance of single carbon atoms in metabolism.
17.
Sarcosine is metabolized to glycine by the enzyme sarcosine dehydrogenase, while glycine-" N "-methyl transferase generates sarcosine from glycine.
18.
Sarcosine is metabolized to glycine by the enzyme sarcosine dehydrogenase, while glycine-" N "-methyl transferase generates sarcosine from glycine.
19.
Sarcosine is metabolized to glycine by the enzyme sarcosine dehydrogenase, while glycine-" N "-methyl transferase generates sarcosine from glycine.
20.
Glycine N-methyltransferase catalyzes the synthesis of N-methylglycine ( sarcosine ) from glycine using S-adenosylmethionine ( SAM ) ( AdoMet ) as the methyl donor.
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