Using a laser-scanning microscope, researchers have observed the severing of nerves in the brains of patients with multiple sclerosis cells, presumably by chemicals in the brain.
12.
It was not until 1978 when Thomas and Christoph Cremer developed the first practical confocal laser scanning microscope and the technique rapidly gained popularity through the 1980s.
13.
Confocal laser scanning microscopes can have a programmable sampling density and very high resolutions while Nipkow and PAM use a fixed sampling density defined by the camera's resolution.
14.
In 1980 he invented a method for the correction of spherical aberration in electron optical systems using sextupoles and, in 1996, Crewe invented a new type of focusing lens for low voltage scanning microscopes.
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"I knew that we'd taken a huge step forward in the ability to control the structure of matter, " said Donald Eigler, a physicist at IBM's Almaden Research Laboratory in San Jose who helped perfect the scanning microscope.
16.
Since a series of pinholes scans an area in parallel each pinhole is allowed to hover over a specific area for a longer amount of time thereby reducing the excitation energy needed to illuminate a sample when compared to laser scanning microscopes.
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Though open less than a month and not yet stocked with its centerpiece _ a $ 200, 000-plus multiphoton scanning microscope that can study cells deep within a tissue sample _ the imaging center already is starting to pay marketing dividends, Crump said.
18.
It is based on the public domain software NIH Image ( now ImageJ from the National Institutes of Health ) and extended to handle scanning microscope images, especially of the SxM formats ( SAM, SCM, SEM, SFM, SLM, SNOM, SPM, STM ), hence its name.
19.
They cite Minsky s patent, thank Steve Baer, at the time a doctoral student at the Albert Einstein School of Medicine in New York City where he developed a confocal line scanning microscope, for suggesting to use a laser with Minsky s microscope and thank Galambos, Hadravsky and Petr�H for discussions leading to the development of their microscope.
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