11. Swine influenza viruses have the ability to bind both types of sialic acid receptors. 12. Metastatic cancer cells often express a high density of sialic acid -rich glycoproteins. 13. This overexpression of sialic acid on surfaces creates a negative charge on cell membranes. 14. Unsurprisingly, sialic acids also play an important role in several human viral infections. 15. The sialidase is one of the most important enzymes of the sialic acid catabolism. 16. It has been demonstrated that human milk contains high levels of sialic acid glycoconjugates. 17. A diet rich in sialic acid was given to newborn piglets for five weeks. 18. ManNAc therapy may increase sialic acid production and subsequently increase sialylation of glomerular proteins. 19. Felin coronavirus infections are therefore sialic acid dependant. 20. Sialic acid -rich glycoproteins ( sialoglycoproteins ) bind selectin in humans and other organisms.
