11. The outer-leaflet, facing the outside environment, contains phosphatidylcholine and sphingomyelin . 12. The daily intake of sphingomyelin for human with Western diet is about 300 mg. 13. Under physiological conditions, only part of the sphingomyelin can be digested and absorbed. 14. Other lipids, such as sphingomyelin , appear to be synthesised at the external leaflet. 15. ENPP7 is the only enzyme that has a type of phospholipase C activity against sphingomyelin . 16. Sphingomyelin undergoes significant interactions with cholesterol.17. Chlorisondamine has been shown to form noncovalent complexes with various biomolecules including sphingomyelin and other associated glycolipids. 18. Lastly, phospholipid such as lecithin, cephalin, and sphingomyelin can also be used as effective emulsifiers. 19. Additionally, it can be converted to sphingomyelin by the addition of a phosphorylcholine headgroup by sphingomyelin synthase. 20. Additionally, it can be converted to sphingomyelin by the addition of a phosphorylcholine headgroup by sphingomyelin synthase.
