11. Other sites of primary tumors have included the submandibular gland and other major and minor salivary glands. 12. The next pair are underneath the jaw, the submandibular glands , these produce both serous fluid and mucus. 13. About 85 % of stones occur in the submandibular gland , and between 5-10 % occur in the parotid gland. 14. Like many ant-eating animals, the numbat has an unusually long, narrow tongue, coated with sticky saliva produced by large submandibular glands . 15. Salivary gland fistulae are almost always related to the parotid gland or duct, although the submandibular gland is rarely the origin. 16. They are found in the submandibular gland , sublingual duct, and the parotid gland, but are more developed in the parotid gland. 17. It represents 28 % of malignant submandibular gland tumors, making it the single most common malignant salivary gland tumor in this region. 18. The concentration of calcium in saliva produced by the submandibular gland is twice that of the saliva produced by the parotid gland. 19. The SLC5A1 cotransporter is mainly expressed in the lumen of the small intestine, kidney, parotid glands, submandibular glands and in the heart. 20. The flow of saliva from the submandibular gland is often against gravity due to variations in the location of the duct orifice.