11. Euphoric recall has been cited as a factor in substance dependence , as well as anger problems. 12. A chemical addiction refers to a physical substance dependence where a behavioral addiction involves a psychological dependence. 13. Recent research has demonstrated that genetic factors play an important role in the vulnerability to substance dependence , 14. Important phases in treating substance dependence include establishing coping mechanisms to deal with the hardships of withdrawal symptoms. 15. It was also found that the most frequent disorders were anxiety disorders, depressive, somatoform and substance dependence disorders. 16. However, there are studies that have found evidence of the influence of genes on vulnerability to substance dependence . 17. Prometa combines three medications as a treatment for substance dependence , which became known as the Prometa Treatment Protocol. 18. While there is anecdotal claims of benefit with ibogaine, data to support its use in substance dependence is poor. 19. Concerned about her substance dependence , Jale's friends from the conservatory took her to the Bak1rk�y Psychiatric Hospital for therapy. 20. The DSM incorporates such conditions under the umbrella category of substance use disorders, which includes substance dependence and substance abuse.
