11. A " substantia nigra," 12. Inactivation of the substantia nigra could prove to be a possible treatment for cocaine addiction. 13. Another arousal system, the dopaminergic system, releases dopamine produced by the substantia nigra. 14. It is also highly expressed in areas of the CNS, including the substantia nigra. 15. These fibers are intimately related to the substantia gelatinosa which is probably the terminal nucleus. 16. It is associated with the degeneration of neurons in the substantia nigra and locus coeruleus. 17. Doctors blame a loss of cells in an area of the brain called the substantia nigra. 18. The substantia nigra is a small midbrain area that forms a component of the basal ganglia. 19. The structural similarity between the substantia nigra and globus pallidus was noted by Mirto in 1896. 20. Research and brain autopsies have implicated both dopaminergic system and iron insufficiency in the substantia nigra.
