11. It is also highly expressed in areas of the CNS, including the substantia nigra . 12. A burned-out substantia nigra is a symptom of Parkinsonism, the disease that afflicts Arthur. 13. In 1791 Samuel Thomas von S�mmerring alluded to this structure, calling it the substantia nigra . 14. It is associated with the degeneration of neurons in the substantia nigra and locus coeruleus. 15. The putamen and caudate both input information from the cerebral cortex, thalamus, and substantia nigra . 16. The subthalamic nucleus'glutamatergic neurons then stimulate the Medial globus pallidus and substantia nigra pars reticulata. 17. Inactivation of the substantia nigra could prove to be a possible treatment for cocaine addiction. 18. Parkinson's disease attacks cells in a tiny portion of the brain called the substantia nigra . 19. Parkinson's disease is the slow and steady loss of dopaminergic neurons in substantia nigra pars compacta. 20. Another important input comes from the substantia nigra , pars reticulata, a component of the basal ganglia.
