11. The toxin-induced contraction was related to generation of thromboxane A 2 from arachidonic acid. 12. It is associated with a deficiency of Thromboxane -A synthase, which produces Thromboxane A2. 13. It is associated with a deficiency of Thromboxane-A synthase, which produces Thromboxane A2. 14. Thromboxane is thought to cause platelets in the blood to stick together, leading to blood clots.15. In this case, the greater aggregation of platelets produce ADP, serotonin, and thromboxane A2. 16. Eikelboom theorized that aspirin did not adequately block thromboxane in some patients because of an underlying genetic mutation. 17. The gene responsible for the thromboxane receptor, TBXA2R is found on chromosome 19 and spans 15 kilobases. 18. It is produced by the oxygenation of arachidonic acid by two enzymes : cycloxygenase and thromboxane A2 synthase. 19. The researchers analyzed urine samples of 5, 529 heart patients in Canada for a chemical byproduct of thromboxane . 20. Testosterone also regulates the population of thromboxane A 2 receptors on megakaryocytes and platelets and hence platelet aggregation in humans.
