Care and caution should always be taken in administering doses of Tincture of Opium, such as the use of a dosage syringe or other suitable measurement device, and by pharmacists in preparing Paregoric from Laudanum, and to note that the dosages noted here refer to Apothecaries weight and fluid measure.
12.
Care and caution should always be taken in administering doses of Tincture of Opium, such as the use of a dosage syringe or other suitable measurement device, and by pharmacists in preparing Paregoric from Laudanum, and to note that the dosages in this article refer to Apothecaries weight and fluid measure.
13.
Tincture of Opium is known as one of many " unapproved drugs " regulated by the U . S . Food and Drug Administration ( FDA ); the marketing and distribution of opium tincture prevails today only because opium tincture was sold prior to the Federal Food, Drug & Cosmetic Act of 1938.
14.
For example, in 1915, Frank S . Betz Co ., a medical supply company in Hammond, Indiana, advertised Tincture of Opium, U . S . P ., for $ 2.90 per lb ., Tincture of Opium Camphorated, U . S . P, for 85 cents per lb ., and Tincture of Opium Deodorized, for $ 2.85 per lb.
15.
For example, in 1915, Frank S . Betz Co ., a medical supply company in Hammond, Indiana, advertised Tincture of Opium, U . S . P ., for $ 2.90 per lb ., Tincture of Opium Camphorated, U . S . P, for 85 cents per lb ., and Tincture of Opium Deodorized, for $ 2.85 per lb.
16.
For example, in 1915, Frank S . Betz Co ., a medical supply company in Hammond, Indiana, advertised Tincture of Opium, U . S . P ., for $ 2.90 per lb ., Tincture of Opium Camphorated, U . S . P, for 85 cents per lb ., and Tincture of Opium Deodorized, for $ 2.85 per lb.
17.
Today, however, the drug is often processed to remove all or most of the noscapine ( also called " narcotine " ) present as this is a strong emetic and does not add appreciably to the analgesic or anti-propulsive properties of opium; the resulting solution is called Denarcotized Tincture of Opium or Deodorized Tincture of Opium ( DTO ).
18.
Today, however, the drug is often processed to remove all or most of the noscapine ( also called " narcotine " ) present as this is a strong emetic and does not add appreciably to the analgesic or anti-propulsive properties of opium; the resulting solution is called Denarcotized Tincture of Opium or Deodorized Tincture of Opium ( DTO ).
19.
For example, in the United Kingdom the formula for Paregoric, B . P . is tincture of opium 5 ml, benzoic acid 500 mg, camphor 300 mg, anise oil 0.3 ml, alcohol ( 60 % ) to 100 ml, and contains about 1 / 30th grain of anhydrous morphine in 60 minims, which is 25 % stronger than Paregoric, U . S . P.
20.
She died suddenly soon afterward, on December 9, 1819 . The records of a Dr . Chapman, who looked after her in her final hours, and who commented just after her death that it was " the first instance he ever knew of hysteria producing death ", reveal that he theorized, despite the absence of any valid evidence, that she had overdosed on laudanum, a concentrated tincture of opium.
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