Furthermore, it has been suggested that as many as 7 out of 10 proteins in glycolysis and 7 out of 8 enzymes of the tricarboxylic acid cycle exhibit moonlighting behavior.
12.
Unlike the latter, the genome of " R . prowazekii ", however, contains a complete set of genes encoding for the tricarboxylic acid cycle and the respiratory chain complex.
13.
This gene encodes one of four nuclear-encoded subunits that comprise succinate dehydrogenase, also known as mitochondrial complex II, a key enzyme complex of the tricarboxylic acid cycle and aerobic respiratory chains of mitochondria.
14.
The generally accepted route for itaconate is via glycolysis, tricarboxylic acid cycle, and a decarboxylation of " cis "-aconitate to itaconate via " cis "-aconitate-decarboxylase.
15.
CoA is important in energy metabolism for pyruvate to enter the tricarboxylic acid cycle ( TCA cycle ) as acetyl-CoA, and for ?-ketoglutarate to be transformed to succinyl-CoA in the cycle.
16.
The mitochondrial isoenzyme is involved in the Krebs Cycle ( also known as the Tricarboxylic Acid Cycle [ TCA ] or the Citric Acid Cycle ), and the cytosolic isoenzyme is involved in the metabolism of amino acids and fumarate.
17.
(" R " )-Methylmalonyl-CoA is converted to succinyl-CoA, an intermediate in the tricarboxylic acid cycle, by methylmalonyl-CoA mutase, an enzyme requiring cobalamin to catalyze the carbon-carbon bond migration.
18.
This occurs because the conversion of propionate into methylmalonyl-Coenzyme A ( a vitamin B-12-dependent reaction ) is rate-limiting and hence the ability of the animal to channel propionate into the tricarboxylic acid cycle is considerably reduced.
19.
This is due to the fact that the beta oxidation of long chain fatty acids with an odd number of carbons produces propionyl-CoA . Most part of this metabolite is transformed into succinyl-CoA, which is the precursor of the tricarboxylic acid cycle.
20.
The degradation of odd chain fatty acids releases Acetyl-CoA and propionyl-CoA . Propionyl-CoA is then converted to succinyl-CoA, and both succinyl-CoA and propionyl-CoA are interjected into the tricarboxylic acid cycle for continued production of reductant.
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