11. From the blood of Bombyx mori, V . von Ducceshi has also obtained a tyrosinase . 12. The activity of tyrosinase is similar to catechol oxidase, a related class of copper oxidase. 13. Polyphenol oxidases are a family of di-copper metalloenzymes that include tyrosinase and catechol oxidase. 14. No mutations of the tyrosinase or " C " gene are known in horses. 15. Copper is needed by the body for a dopamine ?-hydroxylase, superoxide dismutase and tyrosinase . 16. In both cases inactive proenzymes such as hemocyanin, tyrosinase , and catcholoxidase must be activated first. 17. CREB and Mitf directly enhance melanin production by raising levels of tyrosinase and other melanin biosynthetic enzymes. 18. An example of such a protein is the enzyme tyrosinase , which is required for melanin production. 19. Normally tyrosinase is produced in minute quantities but its levels are very much elevated in melanoma cells. 20. The mechanism of action of BW-723C86 is decreasing the inhibits the activity of tyrosinase . }}
