Within stable gene deserts, although the ends contain very high levels of GC content, the main bulk of the DNA contains even less GC content than observed in variable gene deserts.
12.
Variable gene deserts with fewer essential genes are thus subjected to frequent SNPs, most of which are neutral . Certain gene deserts are heavy regulators, while others may be deleted without any effect.
13.
GC content is therefore indication for the presence of coding or regulatory processes in DNA . A comparison GC contents and recombination rates between stable and variable gene deserts separated by a coding gene.
14.
Sulston and Waterston report that the two sets of genes have different locations on the worm's chromosomes, with the older, conserved genes lying in the central region of chromosomes and the more variable genes being positioned toward the two ends.
15.
It is possible that since most variable gene deserts have regulatory elements that can act at a distance, conservation of the entire gene desert into a sytenic locus would not have been necessary, so long as these regulatory elements themselves were conserved as units.
16.
Although this effect should theoretically be amplified through the even lower GC-content in variable gene deserts ( thereby truly minimalizing gene density ), the gene conservation rates in variable gene deserts are even lower than observed in stable gene deserts in fact, the rate is far lower than the rest of the genome.
17.
Although this effect should theoretically be amplified through the even lower GC-content in variable gene deserts ( thereby truly minimalizing gene density ), the gene conservation rates in variable gene deserts are even lower than observed in stable gene deserts in fact, the rate is far lower than the rest of the genome.
18.
His studies of the amino acid sequences of immunoglobulins ( also known as antibodies ) helped to fuel the 1970s debate regarding the generation of immune diversity and supported the hypothesis advanced by Bill Dreyer that immunoglobulin ( antibody ) chains are encoded by two separate genes ( a constant and a variable gene ).
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