11. Vasodilators are conventional drugs that cause the blood vessels to relax and widen.12. Prostacyclins are powerful locally acting vasodilators and inhibit the aggregation of blood platelets. 13. In 1952 researchers at Ciba discovered the first orally available vasodilator , hydralazine. 14. Decreased tissue oxygen content and increased tissue CO 2 content act as vasodilators . 15. Patients with PAH produce less NO and others vasodilators and produce more vasoconstrictors. 16. They are known to induce behavioral responses and function as vasodilators and secretagogues. 17. Individuals with chronic MI can be treated with vasodilators as well to decrease afterload. 18. Vasodilators , such as acepromazine, can help improve blood flow to the muscles.19. The effect of nicorandil as a vasodilator is mainly attributed to its nitrate property. 20. Drug treatment includes the rapidly acting vasodilators , including sublingual nitrates or oral clonidine.
