11. Enzymes like pepsin are created in the form of pepsinogen, an inactive zymogen . 12. The protein of MMP7 is secreted as zymogen . 13. This type of inactive precursor to an enzyme is known as a zymogen or proenzyme. 14. In bacteria, a similar strategy of employing an inactive zymogen or prezymogen is used. 15. Phenoloxidase is synthesized by zymogens and are activated by cleaving a N-terminal peptide. 16. Enzyme precursors are called zymogens or proenzymes. 17. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. 18. TTSPs are synthesized as single chain zymogens with N-terminal propeptide sequences of different lengths. 19. This mechanism occurs in the pancreas, which synthesises many digestive precursor enzymes known as zymogens . 20. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum.
