21. ACTH is a widely-used drug to treat rheumatoid arthritis and other disorders22. Potassium loading also increases ACTH and cortisol in humans. 23. Two of these are adrenocorticotropic hormone ( ACTH ) and follicle stimulating hormone. 24. ACTH stimulates uptake of cholesterol and synthesis of pregnenolone.25. Reducing ACTH also reduces the stimulus for continued hyperplasia and overproduction of androgens. 26. Adrenocorticotrophic hormone ( ACTH ) can also upregulate NGF expression in the brain. 27. ACTH elevation causes the adrenal cortex to release cortisol.28. No significant changes were observed in renin, ACTH , or cortisol levels. 29. In a normal horse, this accounts for the majority of ACTH production. 30. The difference in MSH and ACTH peptides that are produced from the precursor proopiomelanocortin.
