Features that support a diagnosis of DBA include the presence of congenital abnormalities, macrocytosis, elevated fetal hemoglobin, and elevated adenosine deaminase levels in red blood cells.
22.
Researchers collected samples of DeSilva's blood, isolated some of her white blood cells, and used a retrovirus to insert a healthy adenosine deaminase ( ADA ) gene into them.
23.
The disease, which usually results in death from infection before age 1, was caused by the lack of a gene that makes an enzyme called adenosine deaminase, or ADA.
24.
This " editor " molecule, RNA adenosine deaminase, according to the theory, can change DNA coding as it is being read, and it is very attracted to the left-handed DNA.
25.
A version of adenosine deaminase can be extracted from cows, but that by itself is not a viable treatment, because the immune system, once repaired, would reject the cow enzyme.
26.
Anderson was the first to try genetic engineering to cure ADA, or adenosine deaminase, form of SCID . His technique changed the gene in blood cells instead of the bone marrow.
27.
"' Double-stranded RNA-specific adenosine deaminase "'is an enzyme that in humans is encoded by the " ADAR " gene ( which stands for " adenosine deaminase acting on RNA " ).
28.
"' Double-stranded RNA-specific adenosine deaminase "'is an enzyme that in humans is encoded by the " ADAR " gene ( which stands for " adenosine deaminase acting on RNA " ).
29.
The " add " gene encodes adenosine deaminase, and the adenine riboswitch that is upstream exposes the gene's start codon and the Shine-Dalgarno sequence when adenine is present in the binding pocket.
30.
Defects in purine catabolism can result in a variety of diseases including gout, which stems from an accumulation of uric acid crystals in various joints, and adenosine deaminase deficiency, which causes immunodeficiency.
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