The hypoplastic-hypomaturation type of amelogenesis imperfecta with "'TDO "'occurs where the tooth enamel depicts a generalized pitted pattern, with open contacts between the teeth as well as an open bite.
22.
Amelogenesis imperfecta, which occurs in between 1 in 718 and 1 in 14, 000 individuals, is a disease in which the enamel does not fully form or forms in insufficient amounts and can fall off a tooth.
23.
In most cases, males with an X-linked form of this condition experience more severe dental abnormalities than affected females . Recent genetic studies suggest that the cause of a significant proportion of amelogenesis imperfecta cases remains to be discovered.
24.
"' Kohlsch�tter-T�nz syndrome "'( KTS ), also called "'Amelo-cerebro-hypohidrotic syndrome "'is a rare inherited syndrome characterized by epilepsy, dementia, intellectual disability, and yellow teeth caused by amelogenesis imperfecta ( abnormal formation of tooth enamel ).
25.
It is phenotypically difficult to diagnose between "'TDO "'and Amelogenesis imperfecta of the hypomaturation-hypoplasia type with taurodontism ( AIHHT ) as they are very closely linked phenotypically during adulthood, and the only distinguishing characteristic is found during genetic analysis by Polymerase Chain Reaction ( PCR ) amplification.
26.
:: : : : I think that this is probably congenital, since I've had it for as long as I remember, unless that bout of meningitis did more than just give me a mild case of " amelogenesis imperfecta " . talk ) 23 : 54, 11 September 2014 ( UTC)
27.
Amelogenesis imperfecta of the hypomaturation type with taurodontism ( AIHHT ) has no hair or bone changes which helps to differentiate between " TDO " cases and AIHHT . Polymerase Chain Reaction also known as PCR is used to amply pieces of DNA and observed for the 141 base pair allele as a result of a deletion of four nucleotides in exon 3 of the DLX-3 gene.
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