Researchers have found these DNA-dense aneuploid tumors are between 10 and 20 times more likely to metastasize, or spread to other parts of the body.
22.
But cancer developed in 21 of the 27 patients with " aneuploid " lesions _ those in which the chromosomes did not divide evenly by 23.
23.
High expression levels are usually seen before the tumor cells become immortalized and aneuploid which can contribute to the chromosomal instability and the aggressive nature of certain cancers.
24.
The underlying cause of aneuploidy remains highly debated; however, entosis is shown to perturb cytokinesis ( cytoplasmic division ) and trigger the formation of aneuploid cells.
25.
The plant forms a genetic complex with two genome types, noted A and B, and diploid, allo-triploid and aneuploid specimens in natural populations.
26.
Li and co-workers found that 40 % of the embryos diagnosed as aneuploid on day 3 turned out to have a euploid inner cell mass at day 6.
27.
Using another genetically engineered mouse that lacks Sgol2 function, and metaphase II leading to single chromatids and physiologically with the formation of aneuploid gametes that give rise to infertility.
28.
If the cell begins mitosis, duplicates its DNA, but is then not able to divide into two separate cells it becomes an aneuploid-containing more chromosomes than normal.
29.
Cells that do not immediately die are likely to create aneuploid cells following subsequent attempts at cell division posing a risk of oncogenesis ( i . e . potentially leading to cancer ).
30.
In these cells chiasma occurs and sister chromatids are partly held together by cohesions; when cell division occurs, the sister chromatids are sheared and mis-segregated which results in an aneuploid state.
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