21. Aneuploidy of autosomes is not well tolerated and usually results in miscarriage of the developing fetus.22. Premature dissociation of the chromatids can lead to chromosome missegregation and aneuploidy in the daughter cells. 23. Turner syndrome certainly is an example of how sex chromosome aneuploidies are milder than autosomal ones. 24. Also, sperm cells with tail-tip swelling patterns generally have lower frequency of aneuploidy . 25. Fetuses with aneuploidy of gene-rich chromosomes such as chromosome 21 instead of the usual two. 26. The most common chromosomal aneuploidy is a trisomy of chromosome 21 which manifests itself as Down syndrome. 27. He supports the aneuploidy hypothesis of cancer that was first proposed in 1914 by Theodor Heinrich Boveri. 28. Differential effect of aneuploidy on the X chromosome and genes with sex-biased expression in Drosophila. 29. When aneuploidy is detected in a fraction of cells in an individual, it is called chromosomal mosaicism. 30. Another PDG work on aneuploidy also received the prize paper of the Society for Assisted Reproductive Technology in 1998
