In 1983, the Russian neurosurgeon Zubkov and colleagues reported the first use of transluminal balloon angioplasty for vasospasm after aneurysmal SAH . The Italian neurosurgeon Dr Guido Guglielmi introduced his endovascular coil treatment in 1991.
22.
This is not to be confused with the so-called " pseudocystic appearance ", mainly radiographically, of other lesions, such as Stafne static bone cyst and aneurysmal bone cyst of the jaws.
23.
Veith has authored or coauthored more than 1, 000 original articles and chapters in medical journals, particularly on limb-salvage surgery and more recently the field of endovascular grafting for traumatic, aneurysmal and occlusive arterial disease.
24.
EG-1962, Edge's lead product candidate, has the potential to fundamentally improve patient outcomes and transform the management of aneurysmal subarachnoid hemorrhage, or aSAH, which is bleeding around the brain due to a ruptured brain aneurysm.
25.
They produce aneurysmal ( bulging ) lesions in the vessel walls which are 1 2 cm in diameter, and have been associated with hypertrophy and dilatation of heart ventricles, thrombosis ( blood clots ) and myocarditis ( inflammation of the heart muscle ).
26.
In the "'phlebectatic "'type, the blood-filled spaces are lined with endothelium and are associated with aneurysmal dilatation of the central vein; in the "'parenchymal "'type, the spaces have no endothelial lining and they usually are associated with haemorrhagic parenchymal necrosis.
27.
These approaches are based on general experience, and the only randomized controlled trial directly comparing the different modalities was performed in relatively well patients with small ( less than 10 mm ) aneurysms of the anterior cerebral artery and anterior communicating artery ( together the " anterior circulation " ), who constitute about 20 percent of all patients with aneurysmal SAH . This trial, the " International Subarachnoid Aneurysm Trial " ( ISAT ), showed that in this group the likelihood of death or being dependent on others for activities of daily living was reduced ( 7.4 percent absolute risk reduction, 23.5 percent relative risk reduction ) if endovascular coiling was used as opposed to surgery.
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