21. Continuous accumulation of ascites can be treated by placing a drain that can be self-drained. 22. CT advantages include its ability to demonstrate evidence of nearby organ invasion, ascites , and metastases. 23. This is used in the treatment of refractory ascites , bleeding from oesophageal varices and hepatorenal syndrome. 24. In severe cases, fluid can shift into the peritoneal cavity ( abdomen ) and cause ascites . 25. This is believed to be a key step in the pathogenesis of ascites in cirrhotics as well. 26. Rarely, when the theca-lutein cysts are stimulated by gonadotropins, massive ascites can result. 27. For example, severe heart failure can cause pulmonary edema, pleural effusions, ascites and peripheral edema. 28. The increased body weight also puts a strain on their hearts and lungs, and ascites often develops. 29. Those with ascites due to cancer ( peritoneal carcinomatosis ) may complain of chronic fatigue or weight loss. 30. If low volume ascites is suspected, then an attempt to elicit the puddle sign may be performed.