People with von Willebrand disease usually experience increased bleeding time, as von Willebrand factor is a platelet adhesion protein, but this is not considered an effective diagnostic test for this condition.
22.
Bleeding time will vary, with location, from a few hours to three days . This is a function of the hirudin and other compounds that reduce the surface tension of the blood.
23.
Tranexamic acid is used in dentistry in the form of a 5 % mouth rinse after extractions or surgery in patients with prolonged bleeding time, e . g . from acquired or inherited disorders.
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A biography called " James Robertson Justice What's The Bleeding Time ? " ( named after a joke in the first Doctor film ) was published by Tomahawk Press on 3 March 2008.
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When the consultant surgeon asks a medical student " What's the bleeding time ? ", he doesn't expect an answer of " talk ) 20 : 19, 8 May 2011 ( UTC)
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Mice that genetically lack MBL or MASP-1 / 3 ( but not MASP-2 / sMAP ) have prolonged bleeding time in experimental injury models, although mice are seen to be normal if there is no insult to the body.
27.
In the 1950s, it became clear that a " plasma factor ", antihemophilic factor ( FVIII ), was decreased in these persons and that Cohn fraction I-0 could correct both the plasma deficiency of FVIII and the prolonged bleeding time.
28.
Abnormalities of the GPIb-V-IX complex result in abnormal appearance and functioning of platelets resulting in Bernard-Soulier syndrome ( BSS ), a condition first described by Bernard J and Soulier J . P . It is a rare hereditary bleeding disorder most commonly with an autosomal recessive inheritance and diagnosed based on prolonged skin-bleeding time, a reduced number of very large platelets ( macrothrombocytopenia ) and defective ristocetin-induced platelet agglutination.
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